The non-vasculitic peripheral and cranial neuropathies are managed first with tricyclic antidepressants or anti-epileptics (e.g. gabapentin, pregabilin, carbamazepine).
For individuals who fail to respond, intravenous immunoglobulin (0.4 g/kg/d for 5 days) may be beneficial. Vasculitic neuropathies are usually treated with corticosteroids and cyclophosphamide, although rituximab is gaining wider acceptance as an alternative to cyclophosphamide.
